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title: CryoCloud v2.16 – Filament support and other workflow improvements
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This update adds filament support along with a range of workflow improvements.

| View in browser Hi there, We’re pleased to share CryoCloud version 2.16, introducing full filament support along with a range of other workflow improvements. 🚀 New Features Filament Support CryoCloud now supports helical reconstruction workflows, including: A new Initial Model Helix 2D job type Filament picking in Topaz, with full visualisation in the job viewer These updates expand CryoCloud’s capabilities to filamentous samples, from picking through reconstruction.   ServalCat ligand restraints Refinement jobs now accept ligand restraint CIF files via the --ligand argument, improving integration for structures containing small molecule ligands. ✨ Improvements Validation for dose\_per\_frame Added min/max validation to the dose\_per\_frame field. This prevents common mistakes where the user may accidentally enter the total dose instead of the dose per frame, leading to motion correction without dose weighting. 🐛 Bug Fixes LocScale Fixed mask path errors, causing completed jobs to lack output.   ServalCat Corrected a typo in command handling: the pixel-size argument is now passed as --pixel\_size (double dash).   MotionCorr CC MotionCorr CC now handles broken or low-frame movies gracefully, skipping affected files with a warning instead of failing the job. Missed previous updates? Catch up on previous releases: CryoCloud v2.9 Release Notes CryoCloud v2.10.1 Release Notes CryoCloud v2.11 Release Notes CryoCloud v2.12 Release Notes CryoCloud v2.13 Release Notes CryoCloud v2.15 Release Notes You’re receiving this email because you have an active CryoCloud account. If you don’t wish to receive future release updates, you can unsubscribe at the bottom of this email. Need help or have feedback? CONTACT SUPPORT CryoCloud, Princetonlaan 6, Utrecht, Utrecht 3584 CB, Netherlands Unsubscribe Manage preferences |
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